Saturday, December 13, 2008

DISCLAIMER: I am not in support of or in protest of products containing or not containing these ingredients. These are compilation of scientific evidence based on the latest research findings.




Toxic? (PART ONE)


Hi Friends! This post is in response to a post by a blog friend of mine,
Small Footprints. It was a post about 6 ingredients in products believed to be toxic. Coming from a
consumer product website, I was a bit skeptical on the facts presented. As a rule of thumb, I always look for references, or clinical studies that support the claims, and there were none on that website. This makes things even more doubtful, and inspired me to do some research on my own to ascertain and dispel the fears people might develop after reading those things. Get ready for a super long post!

The 6 sources I used for research are reliable sources, such as:

I. The
U.S. Environmental Protection Agency (EPA),

II. The
Hazardous Substances Data Bank (HSDB), which is a database of summaries of peer-reviewed literature,

III. The
Registry of Toxic Effects of Chemical Substances (RTECS), which is a database of toxic effects that are not peer-reviewed,

IV. The US FDA's
CFSAN, specifically the Office of Cosmetics and Colors,

V. The
Household Products Database of the U.S. Department of Health and Human Services, and

VI. The
ESIS (European chemical Substances Information System) of the Consumer Products Safety & Quality (CPS&Q) Unit, formerly known as the European Chemicals Bureau (ECB), which is part of the Institute for Health and Consumer Protection (IHCP), one of the 7 scientific institutes in the European Commission's Joint Research Centre (JRC).


1. Diethanolamine (DEA)

DEA is found in shampoos, cosmetics and drugs. DEA & DEA-related ingredients function as emulsifiers or foaming agents in cosmetics, or to adjust a product's pH (acidity). Limited information is available on the health effects of DEA. Here are the 7 truths or facts about DEA:

(i) Acute or short-term inhalation exposure to diethanolamine in humans may result in irritation of the nose and throat.

(ii) Dermal exposure might irritate the skin.

(iii) No info is available on the chronic (long-term), reproductive, developmental, or carcinogenic effects of DEA in humans.

(iv) Animal studies have reported effects on the liver, kidney, blood, and central nervous system (CNS) from chronic oral exposure to DEA.

(v)
The National Toxicology Program (NTP) completed a study in 1998 that found an association between the topical application of DEA & certain DEA-related ingredients and cancer in laboratory animals (mice). For the DEA-related ingredients, the NTP study suggests that the carcinogenic response is linked to possible residual levels of DEA. The NTP study did not establish a link between DEA and the risk of cancer in humans.

(vi) EPA has not classified DEA for carcinogenicity.

(vii) FDA believes that at the present time there is no reason for consumers to be alarmed based on the use of these substances in cosmetics. If FDA determines that a health hazard exists, the agency will advise the industry and the public and will consider its legal options under the authority of the
Food, Drug and Cosmetic Act in protecting the health and welfare of consumers.

Based on the facts available, I don't think anyone should be in fear of using products containing DEA. Besides, if you must know, more than 90% of shampoos and cosmetics available in the market currently contain DEA and/or DEA-related ingredients.


2. Polypropylene (PP)

Is PP really present in lipsticks, mascaras, baby soaps, eye shadows? I tried searching hard for information relating to the use of PP in these products but could not find any. The only thing I could find was the use of PP for the lipstick holder/tube's cover, e.g. the Aveda brand. It's not used in the lipstick itself. And the same for the mascara, PP is used as the interior bottle, not in the mascara itself. And the bag used to hold the baby soap. And the handle of the eye shadow.

PP is a thermoplastic polymer, made by the chemical industry and used in a wide variety of applications, including packaging, textiles (e.g. ropes, Under Armour, thermal underwear and carpets), stationery, plastic parts and reusable containers of various types, laboratory equipment, loudspeakers, automotive components, and polymer banknotes. PP is rugged and unusually resistant to many chemical solvents, bases and acids. Melting point of PP is ~ 160 °C. Polypropene is commonly recycled, and has the number "5" as its recycling symbol.

Here's an example of the usage of PP in a very commonly used product - the PP lid of a Tic Tacs box, with a living hinge and the resin identification code under its flap. I think if you look closely, you could make out the recycling symbol and the number "5" in the centre of that symbol.


Is it because PP could "leak" into the product itself, and hence the issue of toxicity? I don't think so. PP is liable to chain degradation (breaking down into single propylenes) from exposure to UV radiation such as that present in sunlight. For external applications, UV-absorbing additives are commonly used, such as carbon black. Anti-oxidants are also normally added to prevent PP degradation.

EPA and FDA has nothing on PP with regards to the use of PP in cosmetics, but many publications on the use of PP in packaging, textiles, stationery, plastic parts, containers, etc.

From the HSDB:
(i) Evidence for carcinogenicity: No data are available in humans.

(ii) Inadequate evidence of carcinogenicity in animals. The agent is not classifiable as to its carcinogenicity to humans.

So is there any concern about PP? Nopey.


3. Sodium Hydroxymethylglycinate

Although this chemical is widely used in many consumer products, there had been little or no health studies or reliable info on the effect of this chemical on the human health. There are also no info available on the HSDB. Furthermore, there are no publication on this from EPA and FDA. The ESIS had
several conclusions:

(i) There is no information in ESIS for this substance with respect to the BPD [Biocidal Products Directive (Directive 98/8/EC)]. A biocide is a chemical substance capable of killing living organisms, usually in a selective way, e.g. pesticides, antimicrobials, etc.


(ii) This substance is not listed in the Annex I of Export and Import of Dangerous Chemicals [Regulation (EC) No 689/2008].

(iii) This substance is not listed in a priority list [as foreseen under Council Regulation (EEC) No 793/93 on the evaluation and control of the risks of existing substances].

Does this speak about the seriousness of the toxicity of this chemical?


Coming up in PART TWO, the next post tomorrow:

4. Sodium Lauryl Sulphate or Sulfate (SLS)

5. Sodium Laureth Sulfate (SLES)

6. Triclosan


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